Neurotoxins for Excessive Sweating (Hyperhidrosis)

Yes. Xeomin and Botox work similarly to other botulinum toxin products by blocking the nerve signals that stimulate sweat glands. Clinical results show significant sweat reduction in treated areas.

Botulinum toxin is FDA-approved for severe underarm hyperhidrosis. Xeomin and Botox are commonly used off-label for excessive sweating and is widely accepted in medical practice.

Results typically last 3–6 months, depending on the treatment area and individual response.

Most patients describe mild discomfort similar to small pinches. We can discuss options to improve comfort for hands and feet.

Pricing depends on the treatment area and number of units required. During your consultation, we provide clear, personalized pricing.

Compensatory sweating is uncommon with localized treatment for hyperhidrosis.

There is minimal downtime. You can typically return to normal activities the same day.

You may be a candidate if:

• You sweat excessively even when not hot or exercising

• Over-the-counter antiperspirants have failed

• Sweating interferes with daily life

At Boutique Injections, we offer Xeomin® for the treatment of excessive sweating (hyperhidrosis). Many patients ask if Botox® is better — here’s what you should know.

Both Botox® and Xeomin® are botulinum toxin type A injectables that:

• Block the nerve signals that activate sweat glands

• Significantly reduce sweat production in the treated area

• Provide temporary relief lasting several months

Both treatments are highly effective for:

• Underarm sweating (axillary hyperhidrosis)

• Hand sweating (palmar hyperhidrosis)

Foot sweating (plantar hyperhidrosis)

What’s the Difference?

Protein Structure

• Botox® contains accessory (complexing) proteins.

• Xeomin® is considered a “naked” neurotoxin — it contains only the active botulinum toxin without accessory proteins.

Some providers prefer Xeomin® for patients who receive regular treatments or who are concerned about potential antibody resistance over time.

FDA Approval

• Botox® is FDA-approved for severe axillary hyperhidrosis.

• Xeomin® is FDA-approved for other medical and cosmetic uses and is commonly used off-label for excessive sweating.

Off-label use is medically accepted and widely practiced when supported by clinical experience.

Dosing & Effectiveness

At our Phoenix med spa:

• Xeomin® is typically dosed at a 1:1 unit conversion with Botox®.

• Onset of results: 3–7 days

• Full results: Approximately 2 weeks

Duration: 3–6 months (often longer for underarms)

• Initial improvement: 3–7 days

• Full results: Approximately 2 weeks

• Duration: 3–6 months (often longer for underarms)

Many of our Phoenix patients schedule maintenance treatments 2–3 times per year for continued relief.